Our Faculty

Aaron Steiner

Assistant Professor

Dyson College of Arts and Sciences

Biology

Location
  • @Pleasantville
    Dyson Hall 221

Education


PhD , University of Pennsylvania School of Medicine , Philadelphia, PA , 2006
Cell and Molecular Biology

BS , Brandeis University , Waltham, MA , 2000
Biology

Publications


Reid, C. D., Steiner, A. B., Yaklichkin, S., Lu, Q., Wang, S., Hennessy, M. & Kessler, D. S. (2016, April (2nd Quarter/Spring) 13). FoxH1 mediates a Grg4 and Smad2 dependent transcriptional switch in Nodal signaling during Xenopus mesoderm development. Developmental Biology. Vol 414 (Issue 1) , pages 34-44. http://www.sciencedirect.com/science/article/pii/S0012160616300239

Steiner, A. B., Kim, T., Cabot, V. & Hudspeth, A. (2014, March 27). Dynamic gene expression by putative hair-cell progenitors during regeneration in the zebrafish lateral line. Proceedings of the National Academy of Sciences. Vol 111 (Issue 14) , pages E1393–E1401. http://www.pnas.org/content/111/14/E1393.long

RESEARCH INTEREST


Dr. Steiner's research focuses on the regeneration of sensory systems, with emphasis on sensory hair cells. These cells transduce mechanical forces in the inner ear into electrical signals that can be received and interpreted by the brain, and are responsible for our senses of hearing and balance. Hair cells are delicate and can be damaged or destroyed by loud noises and certain medicinal drugs. In humans and other mammals these cells are not naturally regenerated, leading to hearing loss. Fishes and other non-mammalian vertebrates, however, naturally regenerate hair cells throughout life. Dr. Steiner uses the zebrafish as a model system to understand the cellular and molecular processes that enable hair-cell regeneration in such animals, with the goal of identifying new routes to inducing hair-cell recovery in the human ear. His group utilizes the tools of molecular biology, advanced microscopic imaging, and large-scale gene expression analysis to reveal and characterize genes that regulate regeneration.

PROFESSIONAL MEMBERSHIPS

  • Society for Developmental Biology , June 2002
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