Dyson College of Arts and Sciences
Dyson Hall 221
PhD , University of Pennsylvania School of Medicine , Philadelphia, PA , 2006
Cell and Molecular Biology
BS , Brandeis University , Waltham, MA , 2000
Reid, C. D., Steiner, A. B., Yaklichkin, S., Lu, Q., Wang, S., Hennessy, M. & Kessler, D. S.
(2016, April (2nd Quarter/Spring) 13).
FoxH1 mediates a Grg4 and Smad2 dependent transcriptional switch in Nodal signaling during Xenopus mesoderm development.
, pages 34-44.
Steiner, A. B., Kim, T., Cabot, V. & Hudspeth, A.
(2014, March 27).
Dynamic gene expression by putative hair-cell progenitors during regeneration in the zebrafish lateral line.
Proceedings of the National Academy of Sciences.
, pages E1393–E1401.
Dr. Steiner's research focuses on the regeneration of sensory systems, with emphasis on sensory hair cells. These cells transduce mechanical forces in the inner ear into electrical signals that can be received and interpreted by the brain, and are responsible for our senses of hearing and balance. Hair cells are delicate and can be damaged or destroyed by loud noises and certain medicinal drugs. In humans and other mammals these cells are not naturally regenerated, leading to hearing loss. Fishes and other non-mammalian vertebrates, however, naturally regenerate hair cells throughout life. Dr. Steiner uses the zebrafish as a model system to understand the cellular and molecular processes that enable hair-cell regeneration in such animals, with the goal of identifying new routes to inducing hair-cell recovery in the human ear. His group utilizes the tools of molecular biology, advanced microscopic imaging, and large-scale gene expression analysis to reveal and characterize genes that regulate regeneration.
Society for Developmental Biology