Our Faculty
Nigel Yarlett
Distinguished Professor
Director
Dyson College of Arts and Sciences
Chemistry and Physical Sciences
Location
- @New York City
41 Park Row 606
Office Hours
Spring 2015
Office Hours
Spring 2015
Office Hours
Spring 2015
- Biography
- Publications & Presentations
- Research & Creative Works
- Professional Contributions & Service
"In the fields of observation chance favors the prepared mind." Louis Pasteur.
Biography
Awarded a Fellow of the Royal Society of Chemistry (2012); Fellow of the Society of Fellows of Pace University (1996); Hutner Prize in Protozoology (1995); Kenan Teaching Award (2003); Lady Glanely Scholarship (1978). Over 100 publications in the area of protozoan biochemistry. Demonstrated the presence of hydrogenosomes in Rumen protozoa and Rumen fungi. The role of oxygen in the resistance of Trichomonas vaginalis to metronidazole. The unique polyamine bichemistry of Trichomonas vaginalis and Cryptosporidium parvum. The ability of oxoboroles to cure mouse model trypanosomiasis. Novel culture method for Cryptosporidium parvum. Funded by the National Institutes of Health; Drugs for Neglected Diseases initiative, and the Bill and Melinda Gates Foundation.
Education
University of Wales Fellowship , Cardiff University, Cardiff, Wales, UK, 1986
Biochemical Parsitology
Visiting Fellow , Cambridge University, United Kingdom, 1986
Anaerobic Biochemistry
Post-Doctoral , Rockefeller University, New York, 1984
Biochemical Cytology
PhD, Cardiff University/Hannah Research Institute, Cardiff, Wales/ Ayr, Scotland, 1982
Biochemistry
BS, Cardiff University, Cardiff, Wales, UK, 1979
Microbiology
Awards and Honors
Royal Society of Chemistry,
March 01,
2012
- Fellow of the Royal Society of Chemistry
Pace University,
May 2003
- Kenan Award for Teaching Excellence
Pace University,
July 1996
- Fellow of the Society of Fellows of Pace University
International Society for Protistology,
June 14,
1996
- Hutner Prize
University of Wales,
September 14,
1978
- Lady Glanely Scholarship
LICENSURES & CERTIFICATES
- NYSDOH,
September 01
- Radiation Safety Officer
University RSO responsible for ensuring compliance with City, State and Federal guidelines. First responder in NYC for radiation emergency.
Publications
Morada, M., Lee, S., Gunther-Cummins, L., Weiss, L., Widmer, G., Tzipori, S. & Yarlett, N. Continuous culture of Cryptosporidium parvum using hollow fiber technology. International Journal of Parasitology. Vol in press
RESEARCH INTEREST
My Research is focused on the biochemistry and molecular biology of parasitic protozoa, particularly Cryptosporidia sp., and Trypanosomes. My research has resulted in the development of a new class of compound, the oxaboroles, to treat human African trypanosomiasis (HAT) that is currently in phase II clinical trials in Africa. I am also developing a novel culture system to facilitate the screening of novel compounds for the treatment of cryptosporidosis..
Grants, Sponsored Research and Contracts
Intellectual Property
Patent: Treatment of diseases caused by parasitic protozoa and fungal diseases by administration of 5'-deoxy-5'-(substituted) ethylthioribose compounds [Non-Provisional]
United States
Patent: Adenosine compounds for the treatment of diseases caused by parasitic protozoa [Non-Provisional]
United States
Patent: 5'Deoxy-5'-(substituted) alkylthioribose compounds and their pharmaceutical compositions. [Non-Provisional]
United States
PROFESSIONAL MEMBERSHIPS
Royal Society of Chemistry[Fellow]
New York Academy of Science
American Society for Biochemistry and Molecular Biology[Member]
International Society for Protistologists[Member at Large, Editorial Board, Treasurer]
Society for General Microbiology[Editor]
