Charlene Hoegler

Charlene Hoegler

Senior Lecturer
UNV 101 advisor and BIO 491 advisor
Dyson College of Arts and Sciences
Biology
Westchester
Room 204
Costello House
NYC
D219
Dyson Hall

Biography

Personal Quote

"Be not weary in well-doing..."

Faculty Bio

Charlene Blando-Hoegler, Ph.D., of the Biology Department, supports the Pace mission of Opportunitas. She enthusiastically shares with students the exciting ideas and possibilities offered in biology. She is President of the Pace University Sigma Xi Chapter (an international scientific society) and coordinates her departments Pre-professional Advisement. She has taught a variety of courses for both majors and non-majors. In collaboration with research colleagues at New York Medical College, Dr. Hoegler studies heart disease and metabolism. She has published posters and articles in FASEB and ABLE Conference journals.

Awards and Honors

  • Pace University, 2012, Pace University Dyson Fellow
  • Dyson College- Pace University, 2006, Dyson College Distinguished Contribution to General Education Award
  • Woodrow Wilson Foundation, 1999, Woodrow Wilson Foundation "Biodiversity Institute" V
  • Woodrow Wilson Foundation, 1998, Woodrow Wilson Foundation "Biodiversity Institute" IV
  • Edvotek Biotechnology Corp., 1997, Edvotek/ Georgetown University Competitive Grant
  • Woodrow Wilson Foundation, 1997, Woodrow Wilson Foundation "Biodiversity Institute" III
  • Woodrow Wilson Foundation, 1996, Woodrow Wilson Foundation "Biodiversity Institute" II
  • Woodrow Wilson Foundation, 1995, Woodrow Wilson Foundation "Biodiversity Institute" I
  • Archdiocese of New York, 1990, Elizabeth Anne Seton Award
  • Cold Spring Harbor Research Institute, 1989, DNA Learning Center Grant at Cold Spring Harbor

Education

BS, Fordham University, Bronx, N.Y.

MS, Fordham University, Bronx, N.Y.

PhD, Fordham University, Bronx, N.Y.

Research and Creative Works

Research Interest

Dr. Hoegler's major interests involve connective tissue changes in arteries following balloon angioplasty and the biochemistry of heart failure. In addition she studies the evolution and development of seeds and seedlings in the families of Brassicaceae and Fabaceae.

Grants, Sponsored Research and Contracts

Biochemistry of Ilyanassa obsoleta (mud snail)
January 2015 - May 2015. Pace University, $1,000.00. Funded. (in process)

Acetylcholinestease and Protease Inhbitors
January 2013 - September 2014. Pace University, $1,300.00. Funded. Previous research has shown that the inclusion of certain protease inhibitor cocktails (PI) in tissue lysates might not completely protect the structural integrity of proteins of interest. The purpose of the present study is to determine whether inclusion of PI’s in the sample protects the functionality of metabolic enzymes of interest. These experiments examine three commercially available PI’s which were added to tissue extracts of Sprague –Dawley rat (rectus abdominis, biceps femoris, small intestine) and canine tissue (right atrium). An assay for the hydrolysis of alpha naphthol acetate tested the efficacy of one endogenous enzyme, acetylcholine esterase (AChE). Our results showed that certain PI’s failed to protect the catalytic activity of this enzyme exposed to hydrolysis by exogenous trypsin. In addition PI’s seem to interfere with the catalytic activity of acetylcholine esterase. It appears that in the case of native proteins, PI’s may inhibit metabolic enzymes via a mode of action similar to one used to interfere with catalytic sites of undesirable proteases.

Courses Taught

Past Courses

BIO 101: General Biology I
BIO 102: General Biology II
BIO 115: Human Sexuality
BIO 123: Biology & Contemporary Society
BIO 152: Anatomy and Physiology I
BIO 153: Anatomy and Physiology II
BIO 170: Spaceship Earth: Sustainabilit
BIO 220: Human Biology & Cntmpry Scty
BIO 231: Genetics
BIO 233: Histology and Histopathology
BIO 254: Basic Microbiology
BIO 264: Microbiology
BIO 395: Independent Study in Biology
BIO 480: Research in Biology
BIO 481: Research in Biology II
BIO 491: Internship in Biology
ENV 221: Envrmntl Sci: Web of Life
ENV 380: Junior Year Research Seminar
ENV 498: Mentoring Seminar
UNV 101: First-year Sem:unversity Commu
UNV 101: First-Year Smnr Unvrsty Cmmnty

Publications and Presentations

Publications

Evo-devo II: Does seedling protein biochemistry reflect plant phylogeny and development?


Evo-devo I: Does seed protein biochemistry reflect plant phylogeny?
(2013, October (4th Quarter/Autumn)). Vol 34 , pages 320.

Versatility of electrophoresis as a tool for inquiry based collaboration in developmental biology and comparative physiology
(2010, July (3rd Quarter/Summer)). Vol 30 , pages 370.

Presentations

Does the maternal genome influence seedling protein biochemistry during plant embryogenesis?
(2015, June). 35th Workshop/ Conference ABLE. Association for Biology Laboratory Education,

Enzyme activities in muscle tissue lysates can be unexpectedly affected by protease inhibitor cocktails
(2015, April). FASEB (Federation of American Societies for Experimental Biology). AAA, APS, ASBMB, ASN, ASIP, ASPET,

Evo-devo: Does seedling protein biochemistry reflect plant phylogeny and development?
(2014, June). 34th Workshop/Conference ABLE. Association for Biology Laboratory Education,

Reflections on the use of protease inhibitor cocktails for preserving protein in tissue lysates.
(2013, April). FASEB (Federation of American Societies for Experimental Biology). AAA, APS, ASBMB, ASN, ASIP, ASPET,

EVO/DEVO: Does the seed’s biochemistry reflect the plant’s phylogeny?
(2012, June 22). 33rd Workshop/ Conference ABLE. Association for Biology Laboratory Education,

Enzyme Activity and Heart Failure I: Do Lactate Dehydrogenase (LDH) and Malate Dehydrogenase (MDH) Isozyme Activities in Several Organs Reflect Pathophysiological Alterations in Heart Failure?
(2011, April). FASEB (Federated Association of the Societies for Experimental Biology). AAA, APS, ASBMB, ASN, ASIP, ASPET,

Relating biochemistry to morphology using IBCL student research in Developmental Biology Part 2: Implementation of the Pedagogy.
(2010, June). 32nd Workshop/ Conference ABLE . Association for Biology Laboratory Education,

Professional Contributions and Service

Professional Memberships

  • National Society for Histotechnology
  • Pace Academy for Applied Environmental Studies [active member & conference organizer]
  • American Association of Anatomists
  • Association for Biological Laboratory Education
  • Sigma Xi: (International Scientific Research Society) [President of Pace U Chapter(#695)]

Department Service

  • Biology Dept Internship Committee [Committee Chair]
  • Equal Employment Opportunity Committee [EEO officer for Biology Dept and Environmental Dept]
  • Biology Dept. Pre-Professional Advising Committee [Faculty Advisor]
  • Sigms Xi, The Scientific Research Committee [Committee Chair]
  • Westchester Science and Engineering Fair (WESEF) [Pace University Liaison to WESEF]

College Service

  • Pace Academy for Applied Environmental Studies Pace Academy for Applied Environmental Studies [Committee Member]
  • Earth Month Coordinating Committee Earth Month Coordinating Committee [Committee Member]
  • Environmental University Day Environmental University Day [Other]
  • Peace, Justice and Sustainability Committee (PJS) Peace, Justice and Sustainability Committee (PJS) [Committee Member]
  • Sigma Xi, The Scientific Research Society Sigma Xi, The Scientific Research Society [Other]

University Service

  • Campus Culture and Activities Committee [Committee Member]