Sergey Kazakov

Sergey Kazakov

Professor
Dyson College of Arts and Sciences
Chemistry and Physical Sciences
Westchester
103
Costello House
NYC
D219
Dyson Hall

Biography

Awards and Honors

  • Pace University, 2023, Pace Undergraduate Student Academic Conference Travel Fund for Joint Presentations with Faculty Mentors (2023)
  • Pace University, 2022, Pace Undergraduate Student Academic Conference Travel Fund For Joint Presentations with Faculty Mentors (2022)
  • Pace University, 2022, Scholarly Research Awards, Kenan Travel Awards, Presidential Release Time Awards (2003-2022)
  • Marquis Who's Who, 2021, Marquis Who's Who 2021 Albert Nelson Marquis Lifetime Achievement Award
  • Pace University, 2021, Pace Undergraduate Student Academic Conference Travel Fund For Joint Presentations with Faculty Mentors (2021)
  • Marquis Who's Who, 2019, Named an official listee in the 2019 edition of Marquis Who's Who in the World
  • American Chemical Society, New York Section, 2019, Certificate for Mentoring for the Annual 67th Undergraduate Research Symposium (2019)
  • Pace University, 2019, Certificate for presentation at the Annual Student & Faculty Pace Research Day (2019)
  • Dyson College, Pace University, 2019, Summer Research Awards (2004-2019)
  • Pace University, 2017, Pace Undergraduate Student Academic Conference Travel Fund For Joint Presentations with Faculty Mentors (2017)
  • Pace University, 2010, Dyson College Faculty Excellence in Scholarship Award (2010)
  • Lund University, Sweden, 2000, The Swedish Institute Scholarships (2000)
  • Lund University, Sweden, 1999, The Swedish Institute Scholarships (1999)
  • Moscow State University, Russia, 1998, Doctor of Physical and Mathematical Sciences

Licensures and Certificates

  • CITI Program and Pace University, Certificate of completion of the training course: CITI Conflict of Interests (2022)
  • Pace University, Certificate of completion of the Active Shooter: Run, Hide, Fight (Full Course) (2021)
  • Pace University, Certificate for successful completion of the Teaching Online Certification Program and for commitment to excellence in teaching (2020)
  • Pace University, Certificate of completion of the course: FERPA Basics (New - 2016) (2020)
  • MDPI, Review Confirmation Certificate for the following MDPI journals: International Journal of Molecular Sciences, Pharmaceutics, Nanomaterials, Gels, Materials (2020)
  • Pace University, Certificate of completion of the course: Harassment & Discrimination Prevention (2019)

Education

Doctor of Physical and Mathematical Sciences, Moscow State University, Moscow, Russia, 1998
Physical Chemistry/Molecular Physics

Research and Creative Works

Research Interest

Hydrogel/lipid membrane assembly: modeling membrane system of cell; hydrogel nanoparticles, lipogels, nanofilms, liposomes. and lipid membrane synthesis manipulation and characterization; synthetic and natural ionic reservoirs; bioanalytical devices, drug delivery and control release systems

Grants, Sponsored Research and Contracts

MRI: Acquisition of high-throughput fluorescence imaging system for undergraduate research and teaching at Pace University (2019-2023)
2019 - 2023. NSF, Federal, $374,000.00. Funded.

Student Instructional Technology Fee Grant (2018)
2018 - 2019. Pace University, $21,530.00. Funded.

Courses Taught

Past Courses

BMB 710: Research I
BMB 711: Research II
CHE 111: General Chemistry I
CHE 112: General Chemistry II
CHE 296: Tpc: Membrne Transport & Ionic
CHE 296: Tpc: Physcl Biochmstry of Memb
CHE 301: Physcl Chem I: Thermodynamics
CHE 301: Physcl Chmstry: Thrmdynmcs
CHE 301: Physical Chemistry I
CHE 302: Physical Chem II (Lecture)
CHE 302: Physical Chemistry II
CHE 329: Adv Biochemistry Laboratory
CHE 370: Adv Biophysical Chem: Membrane
CHE 392: Chemistry Seminar I
CHE 480: Research in Chemistry
CHE 492: Chemistry Seminar II
ENS 792: Rsrch in Envrnmntl Sci I
PHY 215: Thermodynamics & Quantum Thry
PHY 215: Topic: Thermodynamics

Publications and Presentations

Publications

Degradation kinetics of disulfide cross-linked microgels: Real-time monitoring by confocal microscopy
(2023, September). Gels. Vol 9 , pages 782 (17 pages). https://www.mdpi.com/2310-2861/9/10/782
DOWNLOAD

Probable mechanisms of doxorubicin antitumor activity enhancement by Ginsenoside Rh2
(2022). Molecules. Vol 27 , pages 628. https://doi.org/10.3390/molecules27030628

Structure–activity relationships and transcriptomic analysis of hypoxia-inducible factor prolyl hydroxylase inhibitors
(2022). Antioxidants. Vol 11 , pages 220. https://doi.org/10.3390/antiox11020220

HIF prolyl hydroxylase inhibitors for COVID-19 treatment: Pros and cons
(2021). Frontiers in Pharmacology. Vol 11 , pages 621054.

Zinc switch in pig heart lipoamide dehydrogenase: Steady-state and transient kinetic studies of the diaphorase reaction
(2020). Biochemistry (Moscow). Vol 85 (Issue 8) , pages 908-919.

Quantitative analysis of cell-based luciferase fusion reporters
(2019). Moscow Univ. Chem. Bull.. Vol 60 (Issue 4) , pages 240-247.

Lipobeads
(2017, September). Dr. Angel Catala (Eds.), In Tech. Vol Liposomes (Issue Ch.3) , pages 49-93.

Hydrogel micro-/nanosphere coated by a lipid bilayer: Preparation and microscopic probing
(2017, February). Gels. Vol 3 (Issue 1) , pages 00007 (17 pages).

Bioactive flavonoids and catechols as Hif1 and Nrf2 protein stabilizers –Implications for Parkinson’s disease
(2016, December). Aging and Disease. Vol 7 (Issue 6) , pages 745-762.

Technological challenges and potential advantages of lipobeads as drug delivery systems
(2016, May). Vol 3 , pages 101-104.

Liposome-nanogel structures for future pharmaceutical applications: An updated review
(2016, March). Current Pharmaceutical Design. Vol 22 (Issue 10) , pages 1391-1413.

Lipobead (lipogel) as a future drug delivery system
(2016, February). Dr. Salam Massadeh (Eds.), Manchester , UK:One Central Press. , pages 85-129.

Electrochemistry of chemically trapped dimeric and monomeric recombinant horseradish peroxidase
(2013). Advances in Biosensors and Bioelectronics (ABB). Vol 2 (Issue 3) , pages 25-34.

Bacilli Spore Properties and Detection Methods in Food and in Medical Settings. In book: Bacterial Spores: Current Research and Applications. Ch14
(2012). Ernesto Abel-Santos (Eds.), Caister Academic Press :. , pages 239-252.

Hydrogel films on optical fiber core: properties, challenges, and prospects for future applications. In book: New Polymers for Special Applications. Ch2
(2012). Ailton De Souza Gomes (Eds.), InTech :. , pages 25-70.

Evanescent wave spectroscopy for studying swelling/de-swelling kinetics of soft matter
(2010). Soft Matter. Vol 6 , pages 1191-1196.

Utilization of an in vivo reporter for high throughput identification of branched small molecule regulators of hypoxic adaptation
(2010). Chemistry and Biology. Vol 17 , pages 380-391.

Phase transitions in smart polymer solutions and light scattering in biotechnology and bioprocessing. In Book: SMART POLYMERS: Application in biotechnology and biomedicine (2007), Taylor & Francis, Ch 1
(2007). I. Galaev & B. Mattiasson (Eds.), . , pages 1-52.

Liposome-nanogel structures for future pharmaceutical applications
(2006). Current Pharmaceutical Design 2006. Vol 12 (Issue 36) , pages 4713-4728.

Presentations

Confocal microscopy for the quantitative study of the mechanism of degradation of redox sensitive microgels
(2023, May). Science Day. Pace University,

Kinetics and mechanism of degradation of the redox-sensitive microgels: A microscopic study by confocal microscopy
(2023, May). Student-Faculty Research Day: 2023 Undergraduate Research and Creative Inquiry Day, Honor College Thesis Defense. Pace University,

Kinetics and mechanism of degradation of disulfide cross-linked microgels explored by confocal microscopy
(2023, May). The 70th Annual Undergraduate Research Symposium (URS) . American Chemical Society,

Real-time tracking of the degradation and consequent phenomena (swelling and erosion) of biodegradable microgels under presence of reducing agents using confocal microscopy
(2023, March). ACS Spring 2023 National Meeting, Division of Colloid and Surface Chemistry, Biomaterials and Biointerfaces. American Chemical Society,

Real-time degradation and swelling of disulfide cross-linked microgels at different concentrations of the reducing agent
(2023, February). The 42nd Annual Meeting of the Society of Fellows. Pace University, Dyson College of Arts and Sciences,

Kinetic analysis of biodegradation of giant lipobeads in the presence of reducing agents: a platform for “smart” anticancer drug and gene delivery
(2022, May 7). The 69th ACS Undergraduate Research Symposium. ACS,

Giant degradable lipobeads with redox-responsive hydrogel core as a “smart” anticancer drug delivery system: A kinetic study
(2022, May 6). 2022 Undergraduate Research & Creative Inquiry Day. Pace University,

Multifunctional lipobeads as a potential drug/gene delivery system: The second-order kinetics of redox-sensitive degradation. (honored as Student Plenary Speaker representing Chemistry Department)
(2022, May 4). Science Day (2022). Pace University,

Wet soft matter (liposomes, microgels, lipobeads) under high vacuum: Scanning electron microscopy study
(2022, March). Pittsburg Conference (PITTCON 2022). ACS,

Lipobeads with disulfide cross-linked poly(acrylamide-co-acrylonitrile) core: A versatile platform for drug and gene delivery (Outstanding poster presentation award)
(2022, March 26). 41st Annual Meeting of Dyson College Society of Fellows . Pace University,

Lipobeads in the presence of reducing agents: Kinetics of degradation
(2022, March 21). The ACS Spring 2022 National Meeting & Expo. ACS,

Disulfide cross-linked poly(acrylamide-co-acrylonitrile) microgels: Synthesis, properties, and de-cross-linking kinetics
(2021, April). The ACS Spring 2021 National Meeting & Expo. ACS,

Lipobeads with degradable hydrogel core explode under presence of reducing agents: An approach to anticancer drug delivery
(2021, March). Pittsburg Conference (PITTCON 2021). ACS,

“Exploding” lipobeads (lipogels) for anticancer drug delivery systems
(2020, May 6). Pace Research Day. Pace University,

Degradability of Redox-Responsive Microgels and Lipobeads Tested by Confocal Microscopy
(2020, March 7). 39th Annual Meeting of Dyson College Society of Fellows . Pace University,

Activation of genetic program: a mechanistic insight
(2019, June). 12th International Conference “Biocatalysis. Fundamentals & Applications”. St. Petersburg, Russia.

Lipobeadal anticancer drug delivery system: New mechanisms of controlled drug release
(2019, June). 12th International Conference “Biocatalysis. Fundamentals & Applications”.. St. Petersburg, Russia.

Temperature sensitive and redox degradable hydrogel cores for drug-delivering lipobeads
(2019, May). 67th Undergraduate Research Symposium. ACS,

Lipobeads with degradable hydrogel cores: On route to anti-cancer drug delivery systems (honored as Student Plenary Speaker representing Chemistry Department)
(2019, May). Science Day (2019). Pace University,

Redox degradable hydrogels and microgel cores for anti-cancer lipobeads
(2019, May). Science Day (2019). Pace University,

“Exploding” lipobeads with controlled drug release in highly reducing environment of cancer cells
(2019, May). The Annual Student & Faculty Pace Research Day . Pace University,

Lipobeads with redox-responsive hydrogel core: Redox degradable bulk hydrogel and microgels synthesized by circulation polymerization
(2019, March). 38th Annual Meeting of Dyson College Society of Fellows. Pace University,

Energetically favorable structural organization of the hydrogel/lipid bilayer assembly as microscopically justified
(2019, March). Pittsburg Conference (PITTCON 2019). ACS,

Lipobeads on hydrophobically modified glass slides through temperature-controlled microscopy
(2018, May). 66th Undergraduate Research Symposium. ACS,

Poly(acrylamide-co-acrylonitrile) hydrogel as a “thermophilic” core of lipobeads
(2018, May). 66th Undergraduate Research Symposium. ACS,

Hydrophobic glass surface to support hydrated soft matter partiles: microgels, lipid vesicles, and lipobeads
(2018, May). Science Day. Pace University,

Structural organization of lipobeads and their constituents using scanning electron microscopy
(2018, May). Science Day. Pace University,

“Thermophilic” microgels prepared by sedimentation polymerization
(2018, May). Science Day. Pace University,

Lipobeads (lipogels): A new anticancer drug delivery system
(2018, May). The Annual Student & Faculty Pace Research Day . Pace University,

Microscopic probing of microgels, liposomes, and lipobeads under high vacuum
(2018, March). 37th Annual Meeting of Dyson College Society of Fellows. Pace University,

Temperature-controlled microscopy of microgels, liposomes, and lipobeads on hydrophobically modified glass slides
(2018, March). 37th Annual Meeting of Dyson College Society of Fellows. Pace University,

“Thermophilic” polymer networks: Optimization of poly(acrylamide-co-acrylonitrile) hydrogel synthesis to provide a larger swelling ability for use as medicine delivery system
(2018, March). 37th Annual Meeting of Dyson College Society of Fellows. Pace University,

Lipobeads: On the way to a bioscopic drug delivery system
(2018, March). Pittsburg Conference (PITTCON 2018). Orlando, FL.

Nanobioscopic lipobead – Encapsulated anticancer drugs
(2017, June 28). BIOCATALYSIS 2017 - 4th International School NANO-2017 . Moscow State University, Russia,

Bioscopic lipobead-encapsulated anticancer drug
(2017, May 8). The Annual Student & Faculty Pace Research Day . Pace University,

Lipid bilayer on the surface of microgels: Fluidity vs. Rigidity
(2017, May 6). 65th Annual ACS Undergraduate Research Symposium. ACS,

Lipid bilayer on the surface of microgels: Fluidity vs. Rigidity
(2017, May 3). Science Day 2017. Pace University,

Lipobeads with "thermophilic" hydrogel core
(2017, May 3). Science Day 2017. Pace University,

Giant lipobeads as a tool to optimize the number of steps in preparation of a new smart drug delivery system
(2017, March 8). Pittsburg Conference (PITTCON). Chicago, IL.

Lipobeads’ preparation and imagining using high pressure scanning electron microscopy
(2017, March 8). Pittsburg Conference (PITTCON). Chicago, IL.

Lipobeads: Effect of lipid bilayer fluidity on formation of unilamellar coating on the microgels
(2017, March 4). 36th Annual Meeting of Dyson College Society of Fellows . Pace University,

Polymerization within giant unilamellar vesicles prepared by gentle hydration of hybrid agarose/lipid films
(2017, March 4). 36th Annual Meeting of Dyson College Society of Fellows. Pace University,

Compatibility of hydrogels and phospholipid bilayer: lipobead preparation by microgel/liposome mixing
(2016, May). Science Day 2016. Pace University,

Technological challenges and potential advantages of lipobeads as drug delivery systems
(2016, May). TechConnect World Innovation Conference and Expo. Washington, DC.

Lipogel-encapsulated anticancer drugs
(2016, April). Dyson Research Day. Pace University,

Lipobeads as a new drug delivery system
(2016, April). The Annual Student & Faculty Pace Research Day . Pace University,

Fluorescent microgels with swelling ability upon temperature increase
(2016, March). 35th Annual Meeting of Dyson College Society of Fellows . Pace University,

Lipobeads: Interaction of lipid bilayer with non-spherical microgels
(2016, March). 35th Annual Meeting of Dyson College Society of Fellows . Pace University,

Concept of lipobeads in the context of encapsulated drug delivery: Technological challenges vs. potential advantages
(2016, March). Pittsburg Conference (PITTCON). Atlanta, GA.

Fluorescent hydrogel exhibiting positive volume phase transition
(2015, May). 63rd Annual ACS Undergraduate Research Symposium . ACS,

Liposome/hydrogel mixing: Approach to the lipogel formation
(2015, May). 63rd Annual ACS Undergraduate Research Symposium. ACS,

Characterization of temperature sensitive, fluorescent lipobeads by optical, fluorescence, and confocal microscopy
(2015, May). Science Day 2015 . Pace University,

Lipobeads – the future drug delivery systems: Preparartion and microscopic characterization of spherical lipobeads with “thermophobic” core
(2015, May). Science Day 2015. Pace University,

”Theromophilic” hydrogels and non-spherical lipobeads on their basis for drug delivery
(2015, May). Science Day 2015. Pace University,

Combination of polymer network and lipid bilayer membrane as the other level of complexity of the drug carrier systems
(2015, April). The 3rd Annual Pace Research Day. Pace University,

Lipobeads with “thermophilic” core: Preparation and properties of fluorescent hydrogel exhibiting positive volume phase transition
(2015, March). 34th Annual Meeting of Dyson College Society of Fellows . Pace University,

Lipobeads with “thermophobic” core: Fluorescent microgels with negative volume phase transition synthesized by inverse suspension polymerization method
(2015, March). 34th Annual Meeting of Dyson College Society of Fellows . Pace University,

Giant lipobeads: Preparation, characterization by confocal microscopy, and mechanisms of controlled release
(2015, March). Pittsburg Conference (PITTCON) . New Orleans, LA.

Hydrogel/lipid bilayer assembly
(2014, April). The 2nd Annual Pace Research Day. Pace University, Pleasantville, NY.

Natural hydrogel/membrane structures and lipogels as drug delivery systems
(2014, March). Pittsburg Conference (PITTCON) . Chicago, IL.

Modeling structural transformations within bacterial spores
(2013). Pittsburg Conference (PITTCON). Philadelphia, PA.

A) Lipogel-encapsulated anticancer drugs, b) Modeling structural transformations within bacterial spores, c) Hydrogel film on optical fiber core
(2013). The 1st Annual Pace Research Day. Pace University, Pleasantville, NY.

Optical microscopy and UV-VIS spectroscopy for determination of concentration and extinction coefficients of bacterial spores in aqueous suspensions
(2012). Pittsburg Conference (PITTCON). Orlando, FL.

Electrochemical mechanics of nanometer-scaled structural layers of bacterial spores
(2010). Nanotechnology Conference (Nanotech). Anaheim, CA.

Professional Contributions and Service

Intellectual Property

Patent: (2011) Kazakov S., Kaholek M., Levon K. Lipobeads and their production. US Patent 7883648

Patent: (2011) Kazakov S., Kaholek M., Levon K. Nanogels and their production using liposomes as reactors. US Patent 7943067

Patent: (2009) Kazakov S., Kaholek M., Levon K. Lipobeads and their production. US Patent 7618565

Professional Memberships

  • (2001 - present) American Chemical Society
  • (2004) The Empire Who’s Who Registry of Executives and Professionals
  • (2007) The Who’s Who Among American Teachers & Educators
  • (2008 - present) Dyson College Society of Fellows
  • (2010) The Marquis Who’s Who in America

Department Service

  • (2006 - present) Forensic Science Advisory Committee [Committee Member]
  • (2010-present) Departmental Strategic Plan Commeittee [Committee Member]
  • (2004-present) Advising students and mentoring student research [Faculty Mentor]
  • (2004-present) Department Search and TAP Committees [Committee Member]
  • (2004-present) Development of courses and educational programs [Committee Member]
  • (2004-present) PhysChemNews Bulletin in Dyson Hall [ Founder and Editor]
  • (2010-2022) Departmental website drafting [Committee Member]

College Service

  • (2021 - present) Pharmaceutical Sciences BS program Committee (2021 - present) Pharmaceutical Sciences BS program Committee [Committee Chair]
  • (2003 - present) Student presentations at the Annual Meetings of the Dyson Society of Fellows, Open Houses, Science and Research Days (2003 - present) Student presentations at the Annual Meetings of the Dyson Society of Fellows, Open Houses, Science and Research Days [Faculty Mentor]

University Service

  • (2022 - present) Technology Committee [Committee Member]
  • (2013 - present) Engineering Taskforce [Task Force Member]
  • (2013 - present) Student presentation at The Annual Student & Faculty Pace Research Day [Faculty Mentor]
  • (2006 - present) Scholarly Research and Kenan Travel Grants Committee [Committee Member]

Professional Service

(2003 - present) Reviewer for 25 academic and professional journals [Reviewer, Journal Article]
Process Biochemistry [Reviewer, Journal Article]
Pharmaceutics [Reviewer, Journal Article]
Current Drug Delivery [Reviewer, Journal Article]
International Journal of Molecular Sciences [Reviewer, Journal Article]
Langmuir [Reviewer, Journal Article]
Pharmaceutics [Reviewer, Journal Article]
Nanomaterials [Reviewer, Journal Article]
Journal of Pharmacy and Pharmacology [Reviewer, Journal Article]
Nanomaterials [Reviewer, Journal Article]
ACS Nano [Reviewer, Journal Article]
Gels [Reviewer, Journal Article]
The Journal of Physical Chemistry [Reviewer, Journal Article]
Clinics in Oncology [Reviewer, Journal Article]
Applied Microbiology and Biotechnology [Reviewer, Journal Article]
Interdisciplinary Problems of Nanotechnology, Biomedicine and Nanotoxicology [Reviewer, Journal Article]
Enzyme and Microbial Technology [Reviewer, Journal Article]